Biomarker Menu

document-download

Download this assay page in pdf format.

Download

ACTH (Adrenalcorticotrophic Hormone)

Analyte: Adrenal Corticotrophic Hormone

Specimen Type: For information on this assay, please contact PBI.

Biological or Clinical Significance:

Determination of Adrenocorticotropic hormone (ACTH) is useful in differentiating between primary and secondary adrenocortical hypo- and hyperfunctional disorders: Addison's disease, Cushing's syndrome, adrenal carcinoma, ectopic ACTH syndrome, and adrenal nodular hyperplasia.

With patients receiving more than 5mg/day of biotin, a sample should be taken no sooner than eight hours after previous dose. Patients treated with monoclonal mouse antibodies may have inaccurate results. High titer of antibodies such as streptavidin and ruthenium may cause interference. Due to its correlation with cortisol levels, ACTH concentration is affected by stress. Any single measure may be within the reference range for patients with increased production (Cushing's disease) or minimal production of ACTH.

Downloadable, Printable Biomarker Menus

Alphabetical Listing

Download PDF

Biomarker Category

Download PDF