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HbA1c (Hemoglobin A1c)

Analyte: Hemoglobin A1c

Specimen Type: EDTA Whole Blood, Inquire for additional option(s)

Optimum Volume: 0.5 mL


2-8°C -20°C -70°C
1 week 6 months 1 year

Reporting units: %

Method: Immunoturbidimetric

Biological or Clinical Significance:

Hemoglobin A1c is produced by nonenzymatic glycosylation of the terminal amino group (valine) of the β chain in hemoglobin. Since the reaction is controlled by mass action and the red cell is permeable to glucose, the quantity of HbA1c formed is directly proportional to the average plasma glucose concentration during the red cell’s 120-day life span. As a consequence of this process, HbA1c constitutes a higher percentage (4-5%) of total hemoglobin in long-term hyperglycemia when compared to normoglycemia.

Principle of Test Method:

The HbA1c assay is an automated immunoturbidimetric method.


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