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Specimen Type: Serum
Optimum Volume: 0.4 mL
|1 day||3 months||3 months|
Reporting units: pg/mL
Biological or Clinical Significance:
Angiopoietin-2 is a protein that in humans is encoded by the ANGPT2 gene. It belongs to the angiopoietin protein family (angiopoietin-1, -2, -3, and -4) which plays an important role in the development and maintenance of blood vessels and the lymphatic system. ANG-2 is composed of an alpha-helix-rich “coiled coil” N-terminal domain and fibrinogen-like C-terminal domain. The angiopoietins serve as ligands for the receptor tyrosine kinases Tie 1 and Tie 2.
Principle of Test Method:
The Ang-2 assay is a chemiluminescent immunoassay. Assay Range: 5.5 - 2,800 pg/mL