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Analyte: Vasclular Endothelial Growth Factor-C
Specimen Type: Serum
Optimum Volume: 0.4 mL
|3 days||3 months||3 months|
Reporting units: pg/mL
Biological or Clinical Significance:
Vascular endothelial growth factor receptor 3 is a protein that in humans is encoded by the FLT4 gene. It belongs to the class III subfamily of receptor tyrosine kinases (RTKs). This receptor contains seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. It regulates VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. VEGF-R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
Principle of Test Method:
The VEGF-R1 assay is a chemiluminescent immunoassay. Detection range 5.4 - 5500 MRD 1:2