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Analyte: Vasclular Endothelial Growth Factor-D
Specimen Type: Serum
Optimum Volume: 0.4 mL
|3 days||6 months||6 months|
Reporting units: pg/mL
Biological or Clinical Significance:
Vascular endothelial growth factor D is a protein that in humans is encoded by the FIGF gene. It belongs to the PDGF/VEGF growth factor family and highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas. VEGF-D regulates angiogenesis and lymphangiogenesis during development and tumor growth, and are characterized by eight conserved cysteine residues that form a cysteine knot structure. It binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
Principle of Test Method:
The VEGF-D assay is a chemiluminescent immunoassay. Detection range 19.5 - 20000 MRD 1:2