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Analyte: Bone Morphogenic Protein-9
Specimen Type: Serum
Optimum Volume: 0.4 mL
|3 days||6 months||6 months|
Reporting units: pg/mL
Biological or Clinical Significance:
Bone Morphogenetic Protein 9 (BMP-9), also known as growth differentiation factor 2 (GDF2), is encoded by the human CDF2 gene. It belongs to the TGF-β cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. BMP-9 can signal through the ALK1 receptor and has been implicated in a number of physiologic events. These include regulation of the hepatic reticuloendothelial system, glucose homeostasis, and iron homeostasis, as well as the inhibition of angiogenesis.
Principle of Test Method:
The BMP-9 assay is a chemiluminescent immunoassay. Assay Range: 2.4 - 2,900 pg/mL