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Biomarker Category: HDL Functionality

CETP Activity (Cholesteryl Ester Transfer Protein)

Analyte: Cholesteryl Ester Transfer Protein- Activity
Specimen Type: EDTA Plasma, Citrate Plasma, Serum
Biological or Clinical Significance:

Plasma cholesteryl ester transfer protein (CETP) facilitates the transfer of cholesteryl ester (CE) from high density lipoprotein (HDL) to apolipoprotein B-containing lipoproteins. Since CETP regulates the plasma...
https://pacbio.com/biomarker/assay-detail/16

CETP Mass (Cholesteryl Ester Transfer Protein)

Analyte: Cholesteryl Ester Transfer Protein - Mass
Specimen Type: Serum, EDTA Plasma, Citrate Plasma
Biological or Clinical Significance:

Plasma cholesteryl ester transfer protein (CETP) facilitates the transfer of cholesteryl ester (CE) from high density lipoprotein (HDL) to apolipoprotein B-containing lipoproteins. Since CETP regulates the plasma...
https://pacbio.com/biomarker/assay-detail/17

Cholesterol Efflux

Analyte: Cholesterol Efflux
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/336

HDL ORAC (Oxygen Radical Absorbance Capacity)

Analyte: Oxygen Radical Absorbance Capacity
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/228

HDL-SAA (HDL Serum Amyloid A)

Analyte: HDL-Serum Amyloid A
Specimen Type: Serum, Inquire for additional option(s)
Biological or Clinical Significance:

Serum Amyloid A (SAA) is an acute-phase protein. During acute events, the rise in SAA levels is one of the most rapid and intense increases of all acute phase proteins. When elevated above normal levels SAA is...
https://pacbio.com/biomarker/assay-detail/222

LCAT Activity (Lecithin-Cholesterol Acyltransferase)

Analyte: Lecithin Cholesterol Acyltransferase Activity
Specimen Type: Serum,EDTA Plasma
Biological or Clinical Significance:

Lecithin-cholesterol acyltransferase (LCAT) is a 63kDa glycoprotein synthesized in the liver, released into the circulation, and primarily activated by apo A-I. LCAT is an enzyme that catalyzes the formation...
https://pacbio.com/biomarker/assay-detail/46

LCAT Mass (Lecithin-Cholesterol Acyltransterase)

Analyte: Lecithin Cholesterol Acyltransferase Mass
Specimen Type: EDTA Plasma (recommended), Serum*
Biological or Clinical Significance:

High density lipoprotein (HDL) plays an important role in reverse cholesterol transport, a process by which excess cholesterol from peripheral tissues is returned to the liver for use or excretion. There is a...
https://pacbio.com/biomarker/assay-detail/128

Lp-PLA2 Activity (Lipoprotein-associated Phospholipase A2)

Analyte: Lipoprotein Associated Phospholipase A2
Specimen Type: EDTA Plasma; Inquire for additional option(s)
Biological or Clinical Significance:

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a calcium-independent serine lipase that is associated with low-density lipoprotein (LDL) in human plasma and serum and is distinct from other phospholipases...
https://pacbio.com/biomarker/assay-detail/48

LpPLA2 Mass (Lipoprotein-associated Phospholipase A2)

Analyte: Lipoprotein-Associated A2 Mass
Specimen Type: Serum, EDTA Plasma
Biological or Clinical Significance:

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a calcium-independent serine lipase that is associated with low-density lipoprotein (LDL) in human plasma and serum and is distinct from other phospholipases,...
https://pacbio.com/biomarker/assay-detail/333

Paraoxonase-1 Activity (PON-1)

Analyte: Paraoxonase-1 Activity
Specimen Type: Serum, Inquire for additional option(s)
Biological or Clinical Significance:

Paraoxonase is a single glycoprotein that is able to hydrolyze aromatic carboxylic acid esters as well as organophosphate compounds. It is closely associated with HDL particles and has a molecular mass of 43...
https://pacbio.com/biomarker/assay-detail/53

Paraoxonase-1 Mass (PON-1)

Analyte: Paraoxonase-1 Mass
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/338

PON-1 Activity (Paraoxonase-1)

Analyte: Paraoxonase-1 Activity
Specimen Type: Serum, Inquire for additional option(s)
Biological or Clinical Significance:

Paraoxonase is a single glycoprotein that is able to hydrolyze aromatic carboxylic acid esters as well as organophosphate compounds. Because of these alternative substrates, this enzyme has been called arylester...
https://pacbio.com/biomarker/assay-detail/246

PON-1 Mass (Paraoxonase-1)

Analyte: Paraoxonase-1 Mass
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/360

Pre β1-HDL

Analyte: Pre ß1 High-Density Lipoprotein
Specimen Type: EDTA Plasma with stabilizer recommended; please contact PBI for collection information
Biological or Clinical Significance:

Pre β1-HDL is a discoid-shaped HDL particle of approximately 67 kDa that migrates with pre-β electrophoretic mobility on agarose gels. It contains apolipoprotein A-I (Apo AI), phospholipids and unesterified...
https://pacbio.com/biomarker/assay-detail/57

sPLA2 Activity (Secretory Phopholipase Type A2)

Analyte: Secretory Phospholipase Type A2 Activity
Specimen Type: EDTA Plasma, Serum
Biological or Clinical Significance:

The phospholipase A2 family of enzymes catalyse the hydrolysis of cellular phospholipids at the sn-2 position to release lysophospholipids and free fatty acids.

Secretory type-IIa phospholipase...
https://pacbio.com/biomarker/assay-detail/67

sPLA2 Mass (Secretory Phopholipase Type A2)

Analyte: Secretory Phospholipase Type A2 Mass
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/432

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