Biomarker Menu

Biomarker Category: Coagulation

D-Dimer

Analyte: D-Dimer
Specimen Type: Citrate Plasma, Heparin Plasma, Inquire for additional option(s)
Biological or Clinical Significance:

Before clot formation, prothrombin must be converted to thrombin. When the level thrombin exceeds the ability of antihrombin and other inhibitors to neutralize it fibrinopeptides are released from the soluble...
https://pacbio.com/biomarker/assay-detail/24

FDP (Fibrinogen Degredation Products)

Analyte: Fibrinogen Degredation Products
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/430

Fibrinogen

Analyte: Fibrinogen
Specimen Type: EDTA Plasma (Preferred), Citrate Plasma (Acceptable)
Biological or Clinical Significance:

Fibrinogen is a soluble precursor of the insoluble fibrin, the major component of blood clots. It is a 340,000 Dalton glycoprotein composed of six subunits. When fibrinogen is activated by the proteolytic enzyme...
https://pacbio.com/biomarker/assay-detail/106

PAI -1 (Plasminogen Activator Inhibitor-1)

Analyte: Plasminogen Activator Inhibitor 1
Specimen Type: Frozen Citrate or EDTA Plasma
Biological or Clinical Significance:

Plasminogen activator inhibitor-1 (PAI – 1) is the principal inhibitor of tissue plasminogen activator and urokinase, the activators of plaminogen and hence fibrinolysis.

PAI-1 is present...
https://pacbio.com/biomarker/assay-detail/152

PAP (Plasmin-alpha2-antiplasmin Complex)

Analyte: Plasmin α2-antiplasmin complex
Specimen Type: EDTA Plasma with inhibitors, P100 Plasma; Please contact PBI for collection instructions
Biological or Clinical Significance:

The removal of polymerized fibrin from the vascular system by proteolytic degradation (fibrinolysis) is important for maintaining the hemostatic balance.  The key enzyme of the fibrinolytic system is plasmin. ...
https://pacbio.com/biomarker/assay-detail/153

TAT (Thrombin-antithrombin Complex)

Analyte: Thrombin-antithrombin Complex
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/341

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