Biomarker Menu

Biomarker Category: Oxidative Stress

ADMA (Asymmetric Dimethylarginine)

Analyte: Asymmetric Dimethyl Arginine
Specimen Type: Serum, EDTA Plasma
Biological or Clinical Significance:

Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of NO synthase. It is formed during proteolysis of methylated proteins and removed by renal excretion or metabolic degradation by the enzyme dimethylarginine...
https://pacbio.com/biomarker/assay-detail/80

Apolipoprotein A-I

Analyte: Apolipoprotein AI
Specimen Type: Serum (preferred), EDTA Plasma
Biological or Clinical Significance:

Apolipoproteins are components of plasma lipoproteins. They play a role in the structure, function, and metabolism of lipoproteins.

Apo A-I, the predominant protein, constitutes approximately 60% of...
https://pacbio.com/biomarker/assay-detail/6

Apolipoprotein A-I, Urine

Analyte: Apolipoprotein AI
Specimen Type: Urine
Biological or Clinical Significance:

Human Apolipoprotein A-I (apo A-I) comprises about 70% of the high-density lipoproteins (HDL) protein mass, while apo A-II makes up another 15 – 20%.  Apo A-I, a 243-amino acid molecule that contains a...
https://pacbio.com/biomarker/assay-detail/357

Ascorbic Acid (Vitamin C)

Analyte: Ascorbic Acid
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/356

8-Hydroxydeoxyguanosine

Analyte: 8-Hydroxydeoxyguanosine
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/358

Isoprostane

Analyte: Isoprostane
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/359

Myeloperoxidase (MPO)

Analyte: Myeloperoxidase
Specimen Type: Heparin Plasma
Biological or Clinical Significance:

MPO is an enzyme that is synthesized and stored within polymorphonuclear leukocytes (PMN’s) and monocytes. MPO generates an array of reactive oxidants and free radical species as part of its role in host defenses....
https://pacbio.com/biomarker/assay-detail/144

OxLDL (Oxidized Low Density Lipoprotein)

Analyte: Oxidized LDL
Specimen Type: Serum, EDTA Plasma
Biological or Clinical Significance:

Lipoprotein measurements are used in the diagnosis and treatment of lipid disorders (such as dyslipidemia in diabetes mellitus), atherosclerosis, and various liver and renal diseases. The oxidative conversion...
https://pacbio.com/biomarker/assay-detail/248

Paraoxonase-1 Activity (PON-1)

Analyte: Paraoxonase-1 Activity
Specimen Type: Serum, Inquire for additional option(s)
Biological or Clinical Significance:

Paraoxonase is a single glycoprotein that is able to hydrolyze aromatic carboxylic acid esters as well as organophosphate compounds. It is closely associated with HDL particles and has a molecular mass of 43...
https://pacbio.com/biomarker/assay-detail/53

Paraoxonase-1 Mass (PON-1)

Analyte: Paraoxonase-1 Mass
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/338

PON-1 Activity (Paraoxonase-1)

Analyte: Paraoxonase-1 Activity
Specimen Type: Serum, Inquire for additional option(s)
Biological or Clinical Significance:

Paraoxonase is a single glycoprotein that is able to hydrolyze aromatic carboxylic acid esters as well as organophosphate compounds. Because of these alternative substrates, this enzyme has been called arylester...
https://pacbio.com/biomarker/assay-detail/246

PON-1 Mass (Paraoxonase-1)

Analyte: Paraoxonase-1 Mass
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/360

Thioredoxin

Analyte: Thioredoxin
Specimen Type: Serum
Biological or Clinical Significance:

Thioredoxins (Trx) are small, multi-functional proteins with oxido-reductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved...
https://pacbio.com/biomarker/assay-detail/232

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