Biomarker Menu

Biomarker Category: Pulmonary

Adiponectin, Total

Analyte: Adiponectin, Total
Specimen Type: Serum, EDTA Plasma, Inquire for additional option(s)
Biological or Clinical Significance:

Adiponectin is an adipocyte-specific protein with potential roles in glucose and lipid homeostasis. It is a member of the TNF superfamily. Adiponectin is induced during adipocyte differentiation and its secretion...
https://pacbio.com/biomarker/assay-detail/2

CTGF (Connective Tissue Growth Factor)

Analyte: Connective Tissue Growth Factor
Specimen Type: Serum
Biological or Clinical Significance:

CTGF, a member of the CCN protein family, is relevant in many physiological and pathological processes.  Both clinical and experimental studies have demonstrated that CTGF is overexpressed in fibrotic human...
https://pacbio.com/biomarker/assay-detail/314

FAS (APO1) (CD95)

Analyte: FAS
Specimen Type: Serum, EDTA Plasma
Biological or Clinical Significance:

Fas (APO-1 or CD95) is a cell-surface receptor that transduces apoptotic signals from Fas ligand (FasL).  It is a glycoprotein with a mass estimated at 43 to 48 kDa.  Fas is a member of the Tumor Necrosis...
https://pacbio.com/biomarker/assay-detail/225

Fibrinogen

Analyte: Fibrinogen
Specimen Type: EDTA Plasma (Preferred), Citrate Plasma (Acceptable)
Biological or Clinical Significance:

Fibrinogen is a soluble precursor of the insoluble fibrin, the major component of blood clots. It is a 340,000 Dalton glycoprotein composed of six subunits. When fibrinogen is activated by the proteolytic enzyme...
https://pacbio.com/biomarker/assay-detail/106

hs-CRP (Highly-Sensitive C-Reactive Protein)

Analyte: C-Reactive Protein
Specimen Type: Serum, EDTA Plasma, Inquire for additional option(s)
Biological or Clinical Significance:

C-reactive protein is the classic acute phase protein in inflammatory reactions. It is synthesized by the liver and consists of five identical polypeptide chains forming a five-membered ring of molar mass 120,000...
https://pacbio.com/biomarker/assay-detail/39

IL-6 (Interleukin-6)

Analyte: Interleukin - 6
Specimen Type: Serum, Inquire for additional option(s)
Biological or Clinical Significance:

Interleukin 6 (IL-6) is a multifunctional cytokine that has a major role in initiation and promulgation of the inflammatory and immune responses.

The biological activities of IL-6 are initiated by...
https://pacbio.com/biomarker/assay-detail/42

KL-6 (Krebs von den Lungen-6)

Analyte: Krebs von den Lungen-6
Specimen Type: Heparin Plasma, Inquire for additional option(s)
Biological or Clinical Significance:

Kerbs von Lungren 6 antigen (KL-6) is a mucinous high-molecular-weight glycoprotein, classified as cluster 9 (MUC1) of lung tumour and differentiation antigens.  KL-6 splits off at the cystine bond near...
https://pacbio.com/biomarker/assay-detail/191

MMP-8 (Matrix Metalloproteinase)

Analyte: Matrix Metalloproteinase-8
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/363

PARC (Pulmonary and Activation-Regulated Cytokine) (CCL-18)

Analyte: Pulmonary and Activation-regulated Cytokine
Specimen Type: Serum, EDTA Plasma
Biological or Clinical Significance:

Chemokines are small cytokines (8 – 10 kDa).  The major role of chemokines is to act as a chemoattractant to guide the migration of cells.  Some chemokines control cells of the immune system during...
https://pacbio.com/biomarker/assay-detail/296

Surfactant Protein A

Analyte: Surfactant Protein A
Specimen Type: Heparin Plasma, Inquire for additional option(s)
Biological or Clinical Significance:

Surfactant Protein A (SP-A; surfactant-associated protein A – SFTPA; pulmonary surfactant-associated protein A – PSPA) is the major protein component of the lung surfactant in mammals.  It belongs, together...
https://pacbio.com/biomarker/assay-detail/215

Surfactant Protein D

Analyte: Surfactant Protein D
Specimen Type: Heparin plasma
Biological or Clinical Significance:

Human surfactant protein D (SP-D) is a member of the collageneous subfamily of glycoproteins and calcium-dependent lectins (collectins).

SP-D is a homotrimeric protein consisting of three 43kDa...
https://pacbio.com/biomarker/assay-detail/216

Tenascin C

Analyte: Tenascin C
Specimen Type: EDTA Plasma
Biological or Clinical Significance:

Tenascin-C is an extracellular matrix glycoprotein that is composed of 210-400 kDa subunits consisting of four domains.  One subunit has a TA domain at the N-terminal end, then an epidermal growth factor-like...
https://pacbio.com/biomarker/assay-detail/364

TGF ß-1 (Transforming Growth Factor ß-1) - Chemi.

Analyte: Transforming Growth Factor ß-1
Specimen Type: Serum
Biological or Clinical Significance:

Transforming Growth Factor Beta 1(TGF-Beta1), is encoded by the human TGF-Beta gene. It a polypeptide member of the transtroming growth factor beta superfamily and cytokines. TGF-beta molecules are proposed to...
https://pacbio.com/biomarker/assay-detail/408

TGF ß-1 (Transforming Growth Factor ß-1) - ELISA

Analyte: Transforming Growth Factor ß-1
Specimen Type: Platlet Poor EDTA Plasma; Please contact PBI for collection instructions
Biological or Clinical Significance:

Transforming growth factor (TGF), a ‘factor’ that promoted the transformation of cultured fibroblasts into a tumor-like phenotype, was subsequently found to be more of a tumor suppressor than tumor promoter...
https://pacbio.com/biomarker/assay-detail/171

TGF ß-1 (Transforming Growth Factor ß-1), Urine

Analyte: Transforming Growth Factor ß-1
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/431

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