Biomarker Menu

Biomarker Category: Lipid Metabolism

C4 (7α-Hydroxy-4-cholestan-3-one)

Analyte: 7a-Hydroxy-4-cholestan-3-one
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/379

CETP Activity (Cholesteryl Ester Transfer Protein)

Analyte: Cholesteryl Ester Transfer Protein- Activity
Specimen Type: EDTA Plasma, Citrate Plasma, Serum
Biological or Clinical Significance:

Plasma cholesteryl ester transfer protein (CETP) facilitates the transfer of cholesteryl ester (CE) from high density lipoprotein (HDL) to apolipoprotein B-containing lipoproteins. Since CETP regulates the plasma...
https://pacbio.com/biomarker/assay-detail/16

CETP Mass (Cholesteryl Ester Transfer Protein)

Analyte: Cholesteryl Ester Transfer Protein - Mass
Specimen Type: Serum, EDTA Plasma, Citrate Plasma
Biological or Clinical Significance:

Plasma cholesteryl ester transfer protein (CETP) facilitates the transfer of cholesteryl ester (CE) from high density lipoprotein (HDL) to apolipoprotein B-containing lipoproteins. Since CETP regulates the plasma...
https://pacbio.com/biomarker/assay-detail/17

7-Ketocholesterol

Analyte: 7-ketocholesterol
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/380

LCAT Activity (Lecithin-Cholesterol Acyltransferase)

Analyte: Lecithin Cholesterol Acyltransferase Activity
Specimen Type: Serum,EDTA Plasma
Biological or Clinical Significance:

Lecithin-cholesterol acyltransferase (LCAT) is a 63kDa glycoprotein synthesized in the liver, released into the circulation, and primarily activated by apo A-I. LCAT is an enzyme that catalyzes the formation...
https://pacbio.com/biomarker/assay-detail/46

LCAT Mass (Lecithin-Cholesterol Acyltransterase)

Analyte: Lecithin Cholesterol Acyltransferase Mass
Specimen Type: EDTA Plasma (recommended), Serum*
Biological or Clinical Significance:

High density lipoprotein (HDL) plays an important role in reverse cholesterol transport, a process by which excess cholesterol from peripheral tissues is returned to the liver for use or excretion. There is a...
https://pacbio.com/biomarker/assay-detail/128

Lp-PLA2 Activity (Lipoprotein-associated Phospholipase A2)

Analyte: Lipoprotein Associated Phospholipase A2
Specimen Type: EDTA Plasma; Inquire for additional option(s)
Biological or Clinical Significance:

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a calcium-independent serine lipase that is associated with low-density lipoprotein (LDL) in human plasma and serum and is distinct from other phospholipases...
https://pacbio.com/biomarker/assay-detail/48

LpPLA2 Mass (Lipoprotein-associated Phospholipase A2)

Analyte: Lipoprotein-Associated A2 Mass
Specimen Type: Serum, EDTA Plasma
Biological or Clinical Significance:

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a calcium-independent serine lipase that is associated with low-density lipoprotein (LDL) in human plasma and serum and is distinct from other phospholipases,...
https://pacbio.com/biomarker/assay-detail/333

PCSK9 (Proprotein Convertase Subtilisin/Keexin Type 9)

Analyte: Proprotein Convertase Subtilisin/Keexin Type 9
Specimen Type: EDTA Plasma, Serum
Biological or Clinical Significance:

Proprotein convertase subtilisin kexin 9 (PCSK9), also named neural apoptosis-regulated convertase 1 (NARC-1), is a member of the proteinase K subfamily of subtilisin-related serine endoproteases.  The full-length...
https://pacbio.com/biomarker/assay-detail/309

Pre β1-HDL

Analyte: Pre ß1 High-Density Lipoprotein
Specimen Type: EDTA Plasma with stabilizer recommended; please contact PBI for collection information
Biological or Clinical Significance:

Pre β1-HDL is a discoid-shaped HDL particle of approximately 67 kDa that migrates with pre-β electrophoretic mobility on agarose gels. It contains apolipoprotein A-I (Apo AI), phospholipids and unesterified...
https://pacbio.com/biomarker/assay-detail/57

sPLA2 Activity (Secretory Phopholipase Type A2)

Analyte: Secretory Phospholipase Type A2 Activity
Specimen Type: EDTA Plasma, Serum
Biological or Clinical Significance:

The phospholipase A2 family of enzymes catalyse the hydrolysis of cellular phospholipids at the sn-2 position to release lysophospholipids and free fatty acids.

Secretory type-IIa phospholipase...
https://pacbio.com/biomarker/assay-detail/67

sPLA2 Mass (Secretory Phopholipase Type A2)

Analyte: Secretory Phospholipase Type A2 Mass
Specimen Type: For information on this assay, please contact PBI.
Biological or Clinical Significance:
https://pacbio.com/biomarker/assay-detail/432

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